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Recent Advances in Cancer Research

A collection of summaries of selected scientific advances from NCI-supported research.

Advances from 2009

DNA Region on Chromosome 1 Is Linked to Neuroblastoma
July 2009
Results of a genome-wide association study indicate that a specific region on human chromosome 1 is associated with the development of neuroblastoma, a childhood cancer that that forms in the adrenal glands and nerve tissue.

Prostate Cancer Screening Did Not Reduce Prostate Cancer Deaths in U.S. Trial
March 2009
Initial results from a large randomized trial conducted in the United States suggest that prostate cancer screening with the digital rectal examination (DRE) and prostate specific antigen (PSA) tests may not reduce the number of deaths from prostate cancer.

Cancer Drug Decreases Recurrence of Gastrointestinal Stromal Tumors
March 2009
Results of a randomized phase III clinical trial show that targeted therapy with the drug imatinib mesylate(Gleevec) reduces disease recurrence following surgery to remove a localized gastrointestinal stromal tumor.

Abnormal Cells Present in Blood Years before Leukemia Is Diagnosed
February 2009
Abnormal white blood cells are present years before diagnosis in virtually all patients with a chronic form of lymphocytic leukemia.

Gene Abnormalities Help Predict Likelihood of Childhood Leukemia Relapse
January 2009
Abnormalities in a gene called IKZF1, which produces a protein that plays an important role in the development of white blood cells, are associated with an increased risk of relapse in patients with childhood acute lymphoblastic leukemia.

Advances from 2008

Large Trial Shows Comparable Accuracy for Virtual Colonoscopy and Standard Colonoscopy
Colorectal – September 2008

Blocking the Activity of a Single Protein Proves Lethal to Myeloma Cells
Multiple Myeloma – July 2008

Changes in Cancer Risk Found for Human Immunodeficiency Virus (HIV)-infected Individuals
HIV Related – July 2008

Low-Dose Drug Combination Cuts Risk of Colon Polyp Recurrence
Colorectal – June 2008

Low Risk Seen in Monitoring, Not Treating, Localized Prostate Cancer
Prostate – May/June 2008

Weekly Paclitaxel Improves Breast Cancer Survival
Breast – April 2008

Genome Study Implicates Human Chromosome 15 in Genetic Susceptibility to Lung Cancer
Lung – April 2008

New Imaging Technology Shows Promise for Diagnosing and Treating Brain Tumors
Brain Tumors – March 2008

Biological Differences Found in Prostate Tumors from African-American and European-American Men
Prostate – February 2008

Advances from 2007

Accuracy of Method to Predict Breast Cancer Risk Increased for African-American Women
Breast – December 2007


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